Ivermectin is effective for COVID-19: meta analysis of 28 studies

Covid Analysis, November 26, 2020 (Version 8, December 28, 2020)

  • 100% of the 28 studies to date report positive effects. Early treatment is more successful, with an estimated reduction of 87% in the effect measured using a random effects meta-analysis, RR 0.13 [0.04-0.40]. Prophylactic use also shows high effectiveness.
  • 100% of the 10 Randomized Controlled Trials (RCTs) report positive effects, with an estimated reduction of 74%, RR 0.26 [0.12-0.56].
  • The probability that an ineffective treatment generated results as positive as the 28 studies to date is estimated to be 1 in 268 million (p= 0.0000000037).
Early treatment 87% improvement RR 0.13 [0.04-0.40]
Late treatment 48% improvement RR 0.52 [0.36-0.74]
Pre-Exposure Prophylaxis 91% improvement RR 0.09 [0.03-0.26]
Post-Exposure Prophylaxis 90% improvement RR 0.10 [0.06-0.17]
Total 28 studies 195 authors 12,560 patients
RCT 10 studies 82 authors 1,759 patients

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