This is perhaps a balance to: IGF-1 and Fasting, which makes sense to me, and is something I’m trying.
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From: Dr. Mercola
A Few Extra Pounds Linked to a Longer Life
Provocative new research involving data from nearly 3 million adults suggests that a having an overweight body mass index (BMI) may be linked to a longer life than one that puts you within a “normal” weight range.
The research, which analyzed 97 studies in all, found that people with BMIs under 30 but above normal (the overweight range) had a 6 percent lower risk of dying from all causes than those who were normal weight, while those whose BMIs fell into the obese range were 18 percent more likely to die of any cause. …
Too much body fat is linked to chronic health problems like high blood pressure, high cholesterol, heart disease, diabetes, and cancer, while too little body fat is also problematic and can cause your body to enter a catabolic state, where muscle protein is used as fuel. …
A general guideline from the American Council on Exercise is as follows:

Classification Women (percent fat) Men (percent fat)
Essential Fat 10-13 percent 2-5 percent
Athletes 14-20 percent 6-13 percent
Fitness 21-24 percent 14-17 percent
Acceptable 25-31 percent 18-24 percent
Obese 32 percent and higher 25 percent and higher

… I suggest you start to look at your weight as less a product of “calories in vs. calories out” and more the result of a faulty “fat switch.” According to Dr. Richard Johnson of the University of Colorado, author of The Fat Switch:
“Those of us who are obese eat more because of a faulty ‘switch’ and exercise less because of a low energy state. If you can learn how to control the specific ‘switch’ located in the powerhouse of each of your cells – the mitochondria – you hold the key to fighting obesity.”
Entire Article Here