The Journal of Steroid Biochemistry and Molecular Biology

Volume 189, May 2019, Pages 228-239
Daily oral dosing of vitamin D3 using 5000 TO 50,000 international units a day in long-term hospitalized patients: Insights from a seven year experience

Patrick J. McCullough a b, Douglas S. Lehrer a b, Jeffrey Amend b

Conclusion

Daily oral intake of vitamin D3 ranging from 5000 IU/d to 60,000 IU/d for several years was well tolerated and safe in both our patients and staff. The mean 25OHD blood levels in our patients appear to take around 12 months to plateau on 5000 IU/d and 10,000 IU. …

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