In the RCTs performed on HCWs, the overall reduction in risk in the population supplemented with vitamin D was approximately 80%.

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Vitamin D supplementation has a protective effect, against the incidence of COVID-19 in RCT studies,

OR 0.403, (95% IC 0.218, 0.747)

In the RCTs performed on HCWs, the overall reduction in risk in the population supplemented with vitamin D was approximately 80%

Against the incidence of COVID-19 in analytical studies

OR = 0.592, (95% IC 0.476–0.736)

Against the incidence of COVID-19 ICU admission

OR 0.317, (95% IC 0.147–0.680).

Our meta-analysis suggests a definitive and significant association between the protective role of vitamin D and COVID-19 incidence and ICU admission.

Preventive Vitamin D Supplementation and Risk for COVID-19 Infection: A Systematic Review and Meta-Analysis

https://www.mdpi.com/2072-6643/16/5/679

(28th Feb 2024)