This review on psoriasis patients says “Yes!”

The Journal of Steroid Biochemistry and Molecular Biology

Daily oral intake of vitamin D3 ranging from 5000 IU/d to 60,000 IU/d for several years was well tolerated and safe in both our patients and staff. The mean 25OHD blood levels in our patients appear to take around 12 months to plateau on 5000 IU/d and 10,000 IU. …

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In this video, Dr. Patrick McCullough, MD, describes how vitamin D status affects T cell activity, and therefore the effectiveness of the immune system in controlling autoimmune diseases and cancers.

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“I’ve been taking 50,000 units per day for years. It helped the skin cancer…. My average hydroxy vitamin D level is in the 200s. My serum calcium levels are always normal.” – Dr. Patrick McCullough

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Dr. Patrick McCullough, MD, shares his patient protocol with vitamin D when asked the question, “What are some of the additional components of your protocol besides vitamin D supplementation?”

Dr. McCullough had worked in a long-term acute care hospital, and now works at a state psychiatric hospital; over half of the patients have stayed there for over a year, some have been there for over 20 years. He has kept vitamin D records among his patients throughout these years, and many of them have been on his vitamin D protocol during the entirety of their care – which has resulted in lots of long-term data on the safety of vitamin D.

In his experience, treating patients with 10,000 IU vitamin D per day, sometimes more, is safe and does not cause kidney stones or renal issues. His findings have been published in his paper “Daily oral dosing of vitamin D3 using 5000 TO 50,000 international units a day in long-term hospitalized patients: Insights from a seven year experience.” [https://www.sciencedirect.com/science…] Dr. McCullough was not going to cause harm – he checked labs twice per week for safety (complete metabolic profiles, intact PTH levels, serum calcium) along with vitamin D levels.

Previous research has shown a huge band of safety with vitamin D. A 2011 publication by Araki et al. [https://pubmed.ncbi.nlm.nih.gov/21917…] reviewed vitamin D toxicity cases that resulted from labeling and manufacturing errors – no deaths were reported, each case resolved with complete recovery.

His patient protocol is to put all patients on 10,000 IU per day, and in his experience, “nothing bad happens – only good things happen!”

vitaminDaction

Dr. Patrick McCullough, MD, discusses the IOM’s vitamin D recommendations in comparison to his clinical experiences with vitamin D. He had been researching the vitamin D literature since 2009 and started treating patients in his hospital with vitamin D before the 2011 IOM report on vitamin D came out. He came up with own protocol based on literature, giving 10,000 IU as his standard of care.